Is Hypoxanthine the future for monitoring endurance performance?

Super interesting article on the use of Hypoxanthine (from sweat) being used as a predictor of performance in athletes.

Having done HR tracking, Power and over the last couple of years, Lactate, it’s always interesting to hear of new methods and advancements in performance, and opportunities to improve metabolic health. So while I am still waiting for a reasonable/practical real-time Lactate monitoring solution, maybe I should skip to the next big thing …

Check it out here: https://pubmed.ncbi.nlm.nih.gov/23670363/

Abstract

Purine metabolism reflects the exercise-induced muscle adaptations and training status. This study evaluated the utility of plasma hypoxanthine in the prediction of actual sport performance. We studied male athletes: 28 triathletes (21.4±2.9 years), 12 long-distance runners (23.2±1.9 years), 13 middle-distance runners (22.9±1.8 years) and 18 sprinters (22.0±2.7 years). Season-best race times were considered, achieved over standard triathlon, 5 000 m, 1 500 m and 100 m, respectively. Incremental treadmill test was administered to determine maximum and “threshold” oxygen uptake. Resting and post-exercise plasma concentrations of hypoxanthine, xanthine, uric acid and lactate were measured as well as resting erythrocyte hypoxanthine-guanine phosphoribosyltransferase activity. Simple and multiple regression analyses were used to identify significant contributors to the variance in performance. Hypoxanthine considered alone explained more variance in triathletes, long-distance runners, middle-distance runners and sprinters (r 2=0.81, 0.81, 0.88 and 0.78, respectively) than models based on aerobic capacity and lactate (R 2=0.51, 0.37, 0.59 and 0.31, respectively). Combining purine metabolites and cardiorespiratory variables resulted in the best prediction (R 2=0.86, 0.93, 0.93 and 0.91; r=0.93, 0.96, 0.96 and 0.95, respectively). In summary, hypoxanthine is a strong predictor of performance in highly trained athletes and its prediction ability is very high regardless of sport specialization, spanning the continuum from speed-power to endurance disciplines. read more

Lithium Labs: 2011 – 2014

I founded Lithium Labs in 2011. It was bootstrapped by the proceeds I received after selling Aschmann Media Group (Social Media Startup). The idea was born by recognizing the impact, and potential, mobile apps could have in the enterprise space. The original mission statement was:

“Lithium Labs provides a full suite of services for designing, developing, implementing and maintaining an enterprise mobility solution. We support all major mobile operating systems and hardware including iPad, iPhone Android, Blackberry, Windows Mobile, Symbol and Intermec.”

The product/application portfolio of the company was seeded by a few mobile apps I had already released, and were being used widely in the SAP space. All of them were free from the various App Stores, the primary objective of these apps were for me to personally learn about the technologies and platforms, and the secondary objective, was to draw awareness to Lithium Labs as a company, and provide an example of what was possible. One of the most popular free apps which I developed under the Lithium Labs portfolio was “SAP Note Viewer”, with 12K downloads. read more

Aero Bottle Holder

Another 3D printed bottle holder for my Canyon Speedmax. This is a raised bottle holder for between your arms and mounts a traditional water bottle cage.

The typical distance between for the mount holes on cages are 64mm. 2 100mm M5 bolts keep the mount attached to a custom made carbon fiber base plate.